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B-Vite Mimics Exercise
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Since 1985,
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October 7, 2013
Dear Valued Subscriber,    

 

Did you know that according to a study in Alcoholism: Clinical and Experimental Research, people consuming cocktails made with artificial sweeteners had breath alcohol concentrations that were 18 percent higher than those imbibing regular mixers - and were less aware that they were becoming impaired?

  

NCI Well Connect Subscribers:

We have updated our Natural Foods Shopping List, which contains foods free of additives, preservatives, chemicals, and trans fats. In addition, many items are gluten-free and kosher.

 

Have a happy, healthy week. Bonnie and Steve Minsky

 

Does This B-Vitamin Mimic Exercise?

Vitamin B3 -- also known as niacin -- and its metabolite nicotinamide added to roundworms' diet caused them to live for about one tenth longer than usual. As an international team of researchers headed by Michael Ristow has now experimentally demonstrated, niacin and nicotinamide take effect by promoting formation of so-called free radicals. He is convinced that small amounts of reactive oxygen species and the oxidative stress they trigger have a health-promoting impact.

  

In earlier studies on humans, Ristow demonstrated that the health-enhancing effect of endurance sports is mediated via an increased formation of reactive oxygen species -- and that antioxidants abolish this effect. Based on the present study, he concludes that niacin brings about a similar metabolic condition to exercise. "Niacin tricks the body into believing that it is exercising -- even when this is not the case," says Ristow. Such compounds are known as "exercise mimetics."

  

The roundworm, which is merely one millimeter in length, can be easily maintained and has a lifespan of only a month, making it the ideal model organism for aging research. The results of the study are of relevance to humans because the metabolic pathway initiated by niacin is very similar in roundworms and higher organisms.

  

The study is based on a particular class of enzymes, sirtuins, which convert niacin into nicotinamide. Genetically modified roundworms that were unable to convert nicotinamide into certain other metabolic products, did not show any lifespan extension, even after overexpression of sirtuins, which otherwise lead to an increased life expectancy. Undoubtedly, some humans will also have a genetic conversion problem, as they do with folic acid. Targeting these individuals may help them live longer.

 

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eNews Updates (access for all)
eNewsThis week's topics:
NCI Well Connect (Subscription Only)
Why NCI Well Connect?
Why NCI Well Connect?

Do you feel overwhelmed by the avalanche of diet and lifestyle information you are exposed to? Do you feel like there is never enough time to read up on all of it? NCI Well Connect can do it for you. 

 

Utilizing our decades of clinical experience to discern what is fact or fiction, we pore over 400 journals and media weekly to find the ideal nutrition and lifestyle tips that will motivate you to adhere to, or improve upon, your wellness goals.

 

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This Week's Topics Are:

  • Healthy Pregnancy Update
  • Scrumptious Fall Salad Recipe
  • Is Veggie Color Important for Cancer Prevention?
  • Flaxseed Shines for a Specific Chronic Issue.
  • Why Is Someone Right or Left-Handed?
  • BPA-Free Canned Food
  • Organic Ready-to-Eat Rice Bowls
  • Nutty Nut Butter
  • Beware of These Manicures.
  • Keep This Produce Out of the Fridge.
  • How Epigenetics Regulates Body Size.
  • eInspire

Please click here to read a recent issue of NCI Well Connect.

 

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Shopping for Trustworthy Foods

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In addition, you have access to our Natural Foods Shopping List, which is updated bimonthly. We take great pains to make sure that every product on our list is vetted for taste and quality. The list includes many gluten-free and kosher items as well.

 

For NCI Well Connect subscribers, you can access it here today or in the Wellness Links section of every eNewsletter.

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