NCI Well Connect Mid-Week Brief
June 6, 2018
Dear Steve, 

DID YOU KNOW that a new study appearing in Environmental Science & Technologyreports that skin is a more important pathway for uptake of cancer-causing compounds produced during barbecuing than inhalation?

They also found that clothing cannot fully protect individuals from this exposure. Yeesh, sorry to all the grillmasters out there.

We are offering a one year NCI Well Connect Membership at 25% OFF at this link! For more details about NCI Well Connect Membership, see below.

Have a happy, healthy day! Steve and Bonnie
Utilizing the Happy, Sleepy Hormone?
Bonnie and Steve: Many of you know tryptophan because of Thanksgiving. We associate it with getting sleepy from eating too much turkey. You know why? The hormone melatonin is produced from tryptophan.

Another reason why properly breaking down tryptophan is so important? It leads to the production of serotonin, the "happy hormone."

To go even further, researchers in a recent study in Nature discovered that if tryptophan, broken down properly into its finest metabolite, serotonin, acts as an anti-inflammatory agent in the brain. The findings provide a clear understanding of how the gut impacts central nervous system resident cells in the brain.

This is what we cite the gut-brain axis often and fondly call the GI tract "second brain."

If the digestive system fails in this process, and serotonin hangs around in the the GI tract, it can become inflamed.

What are the two main reason why tryptophan is not broken down properly into serotonin and melatonin?

1) Dysfunctional microflora, stemming from too many rounds of antibiotics, chronic PPI reflux med use, food intolerances, and overall poor diet are the main offenders, but there are many more.

Beneficial microflora produces enzymes, B-vitamins, and other neurotransmitter-friendly substances that encourage the transfer from tryptophan into serotonin and melatonin. If the beneficial microflora does not exist, your gut and brain suffer.

2) Genetic mutations, such as those that exist in the TPH2 pathway, impedes the breakdown of L-Tryptophan into 5-Hydroxytryptophan (5-HTP), which then turns into serotonin.

In clients with a partial or full mutation of this pathway that is expressing itself negatively, gastrointestinal issues, depression, sleep disorders, among others, are commonplace.

Knowing the function of this genetic pathway can be very helpful for not only your nutritionist, but your internist, mental health, and gastrointestinal health professional.

We test for the TPH2 pathway in our Pure Genomics report.
Summer Dessert Recipe 
This article is reserved for NCI Well Connect Members. You can get this article by signing up for NCI Well Connect at 25% off here today!
Genetic Wellness Screening 

Pure Genomics, our genetic wellness screening, covers 32 impeccably well-researched genes in seven categories:
  1. Methylation
  2. Vitamins and Minerals
  3. Detoxification
  4. Weight Management
  5. Cognitive Health and Memory
  6. Blood Sugar Balance
  7. Immune Health
Pure Genomics tips the balance toward optimal wellness. It only takes four simple steps to get started:
  1. Order a genetic kit from or
  2. Send your saliva sample back to 23andMe or Ancestry. They will email you when your results are ready.
  3. Download your raw genetic data file to your computer. Email us the data file.
  4. We generate your Pure Genomics report and contact you with the next step.
Email Steve for further questions or clarification.
NCI Well Connect Member Benefits 

One Year Membership Is Open to Clients and Non-Clients.
Membership Includes:
  1. Free 45 Minute Pure Genomics Screening & Consultation
  2. Twice Weekly eNewsletters. Long-form issue on Monday and mid-week brief on Wednesday.
  3. Self-Help Action Plans. Access to two titles per month from our 43 title self-help Action Plan Library. Full library of titles here.
  4. Natural Foods Shopping List. Meticulously vetted, high quality food and beverages we recommend to our clients. Gluten-free, corn-free, and kosher pareve items included. Updated quarterly.
We appreciate your continued patronage and support.

Need to search for information from past issues? Type in the word(s) in the google search box at this link.

Have a happy, healthy day,

Bonnie, Steve, Carolyn, Lilo, Elizabeth, Sharron, and Lori (not pictured)
(847) 498 3422

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