NCI Well Connect
August 20, 2018
Dear Steve, 

There will be no NCI Well Connect long-form issue today.

Have a happy, healthy day! Steve and Bonnie
Dangerous Probiotic Trend
Steve and Bonnie: Probiotics have been a public health victory for millions. However, too much of a good thing can be dangerous. Here's the latest example.

UAS Life Sciences, the makers of UP4 Daily, just discontinued the product. Why do you ask? Simply, the dosage was too low. UAS did not replace it with anything else. All their other products are at higher dosages. This is a maddening development not just limited to UAS Life Sciences. Many other manufacturers have already done this with their probiotics.

We have an apples to apples replacement that we love. We will get to that later. 

Why are we opposed to ever-growing dosages in probiotic supplements?
Probiotics are an essential part of most supplemental regimes, simply because we do so many things in our modern lifestyles that deplete good flora. That said, when we started recommending probiotics over 30 years ago, the dosages were small, well tolerated, and were able to be taken daily.

We consider 15 billion units of flora to be the upper level of daily intake. For many, that is now considered a very low dosage. What's worse is that many products are becoming what we call, "throw everything in but the kitchen sink" probiotics. These products contain anywhere form 5 to 15 strains of probiotics. The thinking is that if you throw enough probiotic strains at the problem, it is bound to help. This is a highly flawed philosophy and can do much more harm than good.

Probiotic strains serve very different purposes. For example, one strain of probiotic is beneficial for IBS, where another strain of probiotic is beneficial for Crohn's disease.

Just like you can develop an overgrowth of bad bacteria, you can develop an overgrowth of beneficial bacteria. Your gut is a delicate balance between good and bad bacteria. We need both! If you consistently bombard your GI tract with high dose probiotics, especially strains that your gut already has enough of, you can develop an overgrowth. Low dose probiotics do not create this issue.

There are numerous cases, especially in individuals with disease, who need high dose probiotics. But this should only be done with someone with expertise with high-dose probiotics.

The last thing we want are probiotics disparaged because the supplement industry is seeking convenience over intelligence. We will continue to only recommend low dose probiotics for daily use.

Three Takeaways
  1. Do not self-prescribe probiotics.
  2. If your probiotic has four or more strains, seek the assistance of a health professional to help you find out why.
  3. If your probiotic has more than 15 billion total flora, seek the assistance of a health professional to help you find out why.
Our Replacement for UP4 Daily
We have been using Klaire Probiotic Complex for over a year and we love it. It is an identical replacement with regard to the two strains and dosage. It is rice-free in addition to being dairy, gluten, and corn-free. It does not contain fructooligosaccharide (FOS), which for some can exacerbate IBS. The only downside is that it requires refrigeration prior to, and after, opening. We could not find a non-refrigerated replacement that met our standards.

Do not hesitate to email questions to Steve.
Steve Authors Genetic Study

FTO Gene Study Results Positive
On the heels of our first-ever analysis of genetic data at Nutritional Concepts, I have followed up these findings with a research study that will be submitted to journals for potential publishing.

As part of my masters degree studies, I was asked to author a study on any wellness topic that interested me. Of course, I thought of you first. I wanted to canvas all relevant data to ascertain if FTO gene mutations increase the risk of overweight and obesity.

FTO gene is one we screen for in our Pure Genomics panel, and is the most researched to date with regard to overweight and obesity. I evaluated 113 studies about the FTO gene, narrowed it down to 55 that met my criteria, and for the paper, could only choose 7 to highlight.

The study does meet all scientific requirements, so for many of you it will be a bland read. I just wanted you to know how important it is that what I recommend to our clients is backed by, and heavily vetted from, research.

If interested, you can click on the title below to read my study:

Do FTO Gene Mutations Raise the Risk of Overweight and Obesity? 
Genetic Wellness Screening
Pure Genomics, our genetic wellness screening, covers 32 impeccably well-researched genes in seven categories:
  1. Methylation
  2. Vitamins and Minerals
  3. Detoxification
  4. Weight Management
  5. Cognitive Health and Memory
  6. Blood Sugar Balance
  7. Immune Health
Pure Genomics tips the balance toward optimal wellness. It only takes four simple steps to get started:
  1. Order a genetic kit from or
  2. Send your saliva sample back to 23andMe or Ancestry. They will email you when your results are ready.
  3. Download your raw genetic data file to your computer. Email us the data file.
  4. We generate your Pure Genomics report and contact you with the next step.
Email Steve for further questions or clarification.
Video: New Relaxation Video
Action Plan of the Month:
Toxin-Free Home
One of the benefits of being a NCI Well Connect Member is that you can request two titles monthly from our our Action Plan Library (44 plans: total value $300). 

This comes in handy when you're are moving into a new or old domicile, renovating, or need ideas for making your existing domicile less toxic. Our Toxin-Free Home Action Plan covers just about everything you can think of! 

Action Plans are free by email request for NCI Well Connect Members or can be ordered separately. To activate your membership, click here.
NCI Well Connect Member Benefits

One Year Membership Is Open to Clients and Non-Clients of our practice. Includes:
  1. Free 45 Minute Pure Genomics Screening & Consultation
  2. Twice Weekly eNewsletters. Long-form issue on Monday and mid-week brief on Wednesday.
  3. Self-Help Action Plans. Access to two titles per month from our 44 title self-help Action Plan Library. Full library of titles here.
  4. Natural Foods Shopping List. Meticulously vetted, high quality food and beverages we recommend to our clients. Gluten-free, corn-free, and kosher pareve items included. Updated quarterly.
Care's Corner Video
Food Intolerance: the Silent Assassin
Food Intolerance: the Silent Assassin
Be Your Own Medical Advocate
Aspirin-Like Substances in My Food
Salicylates in My Food? What Are Those?
Wellness Services Menu
We have a multitude of options for simple fine-tuning or the toughest cases.
  • Full Wellness Evaluation (with bloodwork)
  • NCI Well Connect Membership
  • Genetic Wellness Evaluation
  • Balanced Eating 101 (focus on eating only)
  • Food Intolerance Screening and Menu Plan Implementation (separate fees)
  • Memory Loss Protocol
  • Dietary Supplement Evaluation
  • Wellness and Lifestyle Coaching Sessions
  • Far Infrared Sauna Treatment
  • Grocery Shopping Tours and Pantry Advice
  • Workplace Wellness Evaluations
  • Chiropractic and Acupuncture

Consulting prices range from $45 to $225. Contact us at 847-498-3422 or email for details.

We appreciate your patronage and support.

Need to search past issues? Type in the word(s) in the google search box at this link.

Have a happy, healthy day,
Bonnie, Steve, Carolyn, Lilo, Elizabeth, Sharron, and Lori
(847) 498-3422  

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