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Nutritional Concepts Mid-Week Brief
September 17, 2014
Dear Valued Subscriber,

Did you know that researchers in Antioxidants & Redox found quercetin is vital to the nuclei of human cells to sense the cell's health and vitality?

 

The research team are the first to record the continual movement cycle of the protein Nrf2, which oscillates in and out of the cell nucleus once every 129 minutes in order to assess and address cell health. When stimulated by a quercetin, Nrf2's cycle sped up to 80 minutes.

 

Have a happy, healthy week. Bonnie and Steve Minsky

The President Is Low in Vitamin D

Steve: After a recent study showing vitamin D's preventive effect against neurological disorders, you'd think that would be enough for a while. Think again. Vitamin D is the gift that keeps on giving.

 

Epidemiology expert Cedric F. Garland, DrPH stated in a recent interview with Medscape, "I can't imagine a public health or clinical rationale for not screening for low circulating 25(OH)D. Testing should be universal. This will prevent hundreds of thousands of cases of serious diseases worldwide annually, beginning with postmenopausal breast cancer and including colon cancer and types 1 and 2 diabetes. Skipping this test would be equivalent to not measuring blood pressure, serum lipids, or weight at an annual exam."

 

Dr. Garland goes on to say that "no one should run a serum 25(OH)D less than 30 ng/mL. This means that two thirds of the US population needs supplementation. You may have noticed that President Obama was recently tested for his vitamin D, and it was 22.9 ng/mL. His physicians wisely decided to treat him, and he is now taking vitamin D. I salute the President's physicians for their clinical acumen in performing this good and noble deed to ensure the health of President Obama. It makes me burst with pride and admiration when physicians act in this way with their patients."

 

Finally, when asked if everyone should be tested like the President, Dr. Garland implored: "Yes, in my judgment. And without delay. We should introduce the population to a new Golden Era of Medicine, based on contemporary scientific discoveries of vitamin D's profound health benefits today rather than waiting for yet another minor increment of confirmation."

 

Our comments can be accessed by NCI Well Connect subscribers.

 

Organic Food Lovers Who Don't Take Themselves Too Seriously.
Organic And I Know It (Sexy And I Know It Parody)
Organic And I Know It
(Sexy And I Know It Parody)
Medication and Supplement Alerts

fda

Bone Drugs

A JAMA Internal Medicine study found that 3 to 4 years of bisphosphonate treatment did not decrease the risk of invasive postmenopausal breast cancer.

 

Colorectal Cancer

The FDA recently approved a new at-home, DNA-based stool test that screens for colorectal cancer with more than 90 percent accuracy.

 

Medicare is proposing that the stool test be covered for people aged 50 to 85 who have no symptoms of colorectal disease and who are at average risk for colon cancer.

 

A study published in the New England Journal of Medicine found Cologuard had a very high accuracy rate in spotting colon cancer. An accurate, noninvasive test would be a huge because one-third of Americans fail to undergo invasive colonoscopy every 10 years starting at age 50.

 

Diet Pill

A new diet pill, Contrave, got approval to be sold in the United States. Contrave is a combination of the antidepressant bupropion and Orexigen's formulation of naltrexone, designed to prevent drug dependence. Because Contrave contains an antidepressant, it will carry a warning about increased risk of suicidal thoughts and behaviors. Check out the details of this drug. Scary, scary stuff. 

 

Sleeping Pills

In a report published last week in BMJ, researchers say that those who have used benzodiazepines showed a 51% higher risk of Alzheimer's Disease. Among people who took the drugs more than 180 days, the risk escalated to about two-fold higher.

 

Statins

A study in the July 30th issue of Clinical Endocrinology concluded that statin use was associated with thyroid cancer in female patients.

 

Sunscreen

An advisory committee has endorsed new safety testing standards proposed by the US Food and Drug Administration for sunscreen ingredients, adding that even more action may be needed to ensure product safety.

 

Most of the active ingredients in sunscreens have been on the market for many years and have never undergone rigorous safety testing.

 

Products like spray-on sunscreen have recently come under scrutiny.

 

Supplements

The Drug-Induced Liver Injury Network (DILIN) conducted a prospective trial at 8 DILIN sites from 2004 to 2013. They enrolled 839 consecutive people with drug-induced liver injury caused by supplements or conventional medications. They excluded acetaminophen-related cases.

 

The liver injury cases included 45 attributed to bodybuilding supplements, 85 attributed to nonbodybuilding supplements, and 709 caused by medications. During the 10-year journal Hepatology study period, the proportion of cases linked to HDS increased from 7% to 20%.

 

There were 50 deaths among the 709 patients with liver injury resulting from conventional medications. There were 2 deaths caused by nonbodybuilding supplements such as herbal EDs, Chinese herbal mixtures, ayurvedic compounds, and various colon and other "cleanse" products.

 

Check the FDA's most recent Medication Safety Update.